Fmoc-Asn(Trt)-OH

Product Name: Fmoc-Asn(Trt)-OH
CAS No.: 132388-59-1
Chemical Name: Fmoc-Asn(Trt)-OH
Synonyms: FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
CBNumber: CB4331632
Molecular Formula: C38H32N2O5
Formula Weight: 596.67
MOL File: 132388-59-1.mol

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Fmoc-Asn(Trt)-OH Property

Melting point:: 201-204 °C(lit.)
Boiling point:: 858.1±65.0 °C(Predicted)
alpha: -16 º (c=1, MeOH)
Density: 1.271±0.06 g/cm3(Predicted)
refractive index: -19 ° (C=1, DMF)
storage temp.: 2-8°C
solubility: <0.00005g/l
pka: 3.79±0.10(Predicted)
form: powder to crystal
color: White to Almost white
optical activity: [α]20/D 15.0±1°, c = 1% in methanol
BRN: 4343823
InChIKey: KJYAFJQCGPUXJY-UUWRZZSWSA-N
SMILES: C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference: 132388-59-1(CAS DataBase Reference)

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Safety

Risk Statements: 53
Safety Statements: 24/25-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 2
F: 3-10
HS Code: 2924 29 70
HazardClass: IRRITANT
Toxicity: LD50 orally in Rabbit: > 2000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52044
Product name: FMOC-Asn(Trt)-OH
Purity: N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging: 25g
Price: $72.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52044
Product name: FMOC-Asn(Trt)-OH
Purity: N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging: 100g
Price: $219
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52044
Product name: FMOC-Asn(Trt)-OH
Purity: N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging: 250g
Price: $467
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52044
Product name: FMOC-Asn(Trt)-OH
Purity: N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging: 1kg
Price: $1620
Updated: 2024/03/01

Sigma-Aldrich

Product number: 47672
Product name: Fmoc-Asn(Trt)-OH
Purity: ≥97.0%
Packaging: 5G
Price: $59.4
Updated: 2024/03/01

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Fmoc-Asn(Trt)-OH Chemical Properties,Usage,Production

Description

Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.

Chemical Properties

white crystal powde

Uses

Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.

Preparation

Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.

Fmoc-Asn(Trt)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Asn(Trt)-OH Suppliers

Americas 1 Belgium 1 Canada 1 China 333 Europe 4 France 2 Germany 5 India 9 Japan 5 South Korea 1 Switzerland 4 United Kingdom 14 United States 54 Global 434

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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ChemPep, Inc.

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Accela ChemBio Inc.

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Cato Research Chemicals Inc.

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Alchem Pharmtech,Inc.

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AB PharmaTech,LLC

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Aladdin Scientific

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View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-L-Asn(Trt)-OH 132388-59-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-12-07

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Fmoc-Asn(trt)-OH 132388-59-1
Price: US $0.00/gram
Min. Order: 25gram
Purity: 99% HPLC
Supply Ability: 25 gram
Release date: 2023-10-16

Hangzhou ICH Biofarm Co., Ltd

Product: Fmoc-N-β-trityl-L-asparagine 132388-59-1
Price: US $0.00/Box
Min. Order: 1Box
Purity: 99%
Supply Ability: 200kg
Release date: 2023-06-26

132388-59-1, Fmoc-Asn(Trt)-OHRelated Search:

Trityl candesartan METHOXYCARBONYLSULFENYL CHLORIDE p-Toluenesulfonic acid Fmoc-Asp(OtBu)-OH 9-Fluorenylmethyl chloroformate Trityl Irbesartan Trityl candesartan cilexetil Nalpha-Fmoc-Ndelta-trityl-L-glutamine D-(-)-Asparagine monohydrate L-Fmoc-Aspartic acid alpha-tert-butyl ester 2-Phenyl-1-propene Fmoc-Lys(Boc)-OH L-Asparagine ASPARAGINASE Triphenylmethyl Chloride CARBONYL SULFIDE Fmoc-Phe-OH N-(9-Fluorenylmethoxycarbonyloxy)succinimide

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FMOC-ASPARAGINE(TRT)

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FMOC-N-GAMMA-XANTHYL-L-ASPARAGINE

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Fmoc-L-Asparagine(Trt)-OH

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Fmoc-Asparagine(Trt)-OH

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(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-4-oxo-4-(tritylaMino)butanoic acid

FMoc-Asn(Tre)

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Fmoc-Asn(Trt)-OH(CAS:132388-59-1)

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FMOC-N-GAMMA-TRITYL-L-ASPARAGINE

FMOC-N-TRITYL-L-ASPARAGINE

FMOC-N-BETA-TRITYL-L-ASPARAGINE

Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine

Nα-Fmoc-Nγ-trityl-L-asparagine

Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine

na-fmoc-N-gamma-trityl-L-asparagine

N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit

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N-FMOC-N4-TRITYL-L-ASPARAGINE

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L-Asparagine N-|beta|-Trityl-15N2-N-alpha-FMOC

L-Asparagin, N(2)-((9H-fluoren-9-ylmethoxy)carbonyl)- N-(triphenylmethyl)-

N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-(TRIPHENYLMETHYL)-L-ASPARAGINE

N-.ALPHA.-FMOC-N-.GAMMA.-XANTHYL-L-ASPARAGINE

N-α-Fmoc-β-trityl-L-asparagine

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N-FMOC-L-ASN(TRT)-OH

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N-ALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-GAMMA-TRITYL-L-ASPARAGINE

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N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA-XANTHYL-L-ASPARAGINE